SHANK3

Postsynaptic scaffold protein SHANK3

AF-Q9BYB0-F1 · v6 · Human reference sequence 1–1,806

Predicted backbone

Drag to rotate, or use the arrow keys on the model. Select a residue below to inspect its pLDDT.

The original model and trace download are linked below.

≥9070–<9050–<70<50

Research links

Autism spectrum disorder

Rare variant study

A family-based study describes rare disruptive SHANK3 variants and chromosomal rearrangements in individuals on the autism spectrum.

Durand et al., 2007

Provenance and confidence

AlphaFold DB prediction by Google DeepMind and EMBL-EBI. The viewer draws a Cα trace derived from the RCSB BinaryCIF copy. We matched the release, residue sequence and mean pLDDT against AlphaFold DB.

Model: AF-Q9BYB0-F1 · v6
Retrieved: 2026-11-14
Mean pLDDT: 52.42 / 100
Residues by band: ≥90 · 348 / 70–<90 · 239 / 50–<70 · 45 / <50 · 1,174
Coordinate SHA-256: d067759cc7051243462be31c96b2e8af42626349bf6f0dbe402c23afca57b281
License: CC BY 4.0

AlphaFold entry and PAE viewer RCSB model BinaryCIF coordinates Trace JSON

Varadi et al. · AlphaFold DB