SLC6A3
Dopamine transporter (DAT)
AF-Q01959-F1 · v6 · Human reference sequence 1–620
Predicted backbone
The original model and trace download are linked below.
≥9070–<9050–<70<50
Research links
Attention-deficit/hyperactivity disorder
Pharmacological target
A PET study in 24 adult men with ADHD related putaminal dopamine-transporter occupancy after methylphenidate to change in cognitive impulsivity.
Experimental structure
Human DAT with methylphenidate, cryo-EM, 2.83 Å. The deposited construct covers 562 residues.
Provenance and confidence
AlphaFold DB prediction by Google DeepMind and EMBL-EBI. The viewer draws a Cα trace derived from the RCSB BinaryCIF copy. We matched the release, residue sequence and mean pLDDT against AlphaFold DB.
- Model
- AF-Q01959-F1 · v6
- Retrieved
- Mean pLDDT
- 86.95 / 100
- Residues by band
- ≥90 · 465 / 70–<90 · 76 / 50–<70 · 9 / <50 · 70
- Coordinate SHA-256
f6ac395b41b1047378944ca9bd2bacdaaaf5e1a3e6f69f786d0e7d18eec5d747- License
- CC BY 4.0