SLC6A4
Serotonin transporter (SERT)
AF-P31645-F1 · v6 · Human reference sequence 1–630
Predicted backbone
≥9070–<9050–<70<50
Research links
Major depressive disorder
Pharmacological target
A human SERT crystal structure resolves binding of an SSRI. This is evidence about a pharmacological target used in depression research.
Experimental structure
Human SERT with S-citalopram, X-ray diffraction, 3.24 Å. The construct is truncated and engineered.
Provenance and confidence
AlphaFold DB prediction by Google DeepMind and EMBL-EBI. The viewer draws a Cα trace derived from the RCSB BinaryCIF copy. We matched the release, residue sequence and mean pLDDT against AlphaFold DB.
- Model
- AF-P31645-F1 · v6
- Retrieved
- Mean pLDDT
- 84.69 / 100
- Residues by band
- ≥90 · 472 / 70–<90 · 65 / 50–<70 · 7 / <50 · 86
- Coordinate SHA-256
6f29b79ecb6ee5adfa82cdb1b9bb881a7422234e1a907654ef1914a83a703857- License
- CC BY 4.0