Psychiatric Genomics Consortium
Download variant-level summary statistics by study. Check the phenotype definition, especially for analyses pooling anxiety disorders. PGC terms restrict redistribution and commercial use without permission.
Data & collaboration
Official routes to summary statistics, cohort data and collaborative research. Each entry specifies how to request or use the resource.
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PGC individual-level data and collaboration
Find the process for proposing a secondary analysis and requesting individual-level data. The consortium has a separate route for contributing a cohort.
ENIGMA Consortium
Working groups share imaging quality-control and analysis protocols. The joining guide explains how to contact a working group and obtain permission from the cohort lead.
UCLA CNP · OpenNeuro
CC0 imaging and participant metadata for ADHD, schizophrenia-spectrum, bipolar disorder and comparison groups. The research desk records a count of the groups in this exact release.
ABCD Study
Longitudinal development, behavior, mental health and imaging data from young people in the United States. Browse the data dictionary before applying. Record-level access requires NBDC Data Use Certification and an eligible institution.
STAR*D
A multisite study of sequential depression treatment. Individual-level data require NDA approval. Define the sample and missing-data rules for each treatment step before analysis.
World Mental Health Surveys
International mental health survey collaboration. The organizations responsible for each national survey govern access to restricted files. The ICPSR series lists harmonized public-use releases for participating countries and their access terms.
National Comorbidity Survey Replication
U.S. household interviews from 2001–2003. Choose public-use DS2. Restricted DS5 requires separate approval. Use the survey weights and the diagnostic definitions in effect at collection.
Autism Brain Imaging Data Exchange I
Multisite resting-state fMRI, structural imaging and phenotypes for autism research. The NITRC route requires registration with the INDI project and compliance with its noncommercial research terms.
Multi-Sensitivity Study
Cross-sectional self-reports on sensory processing sensitivity, rejection sensitivity, psychological distress and social support in U.S. adults. The open data and codebook are available under CC BY 4.0.
EMBARC
A multisite study with a major depression treatment group and healthy controls. Clinical assessments, EEG and MRI support studies of treatment response. Record-level access requires NDA approval.
CAN-BIND 1
A depression biomarker study from six Canadian sites. Phase 1 includes baseline and week 2–8 follow-up measures, with clinical assessments and imaging. Request controlled data through Brain-CODE.
National Health Interview Survey 2022
Provides two-week anxiety and depression symptom responses from the GAD-7 and PHQ-8, with complex survey weights. The CDC provides public-use files and documentation. Interpret the scales as symptom measures.
NESARC-III
AUDADIS-5 interviews with U.S. adults support studies of how depression and anxiety co-occur with substance use. Apply through dbGaP for individual-level phenotypes. Eligibility and an institutional data use agreement are required.
National Comorbidity Survey Adolescent Supplement
U.S. survey of adolescents aged 13–17 from 2001–2004. It includes DSM-IV variables derived from adolescent and parent reports, with survey weights. Public-use files are available to the public. Restricted files require separate approval.
ADHD-200 Preprocessed
Public preprocessing outputs from the ADHD-200 imaging collection. Compare derivatives by pipeline and processing strategy. The download guide lists a public storage route and a separate NITRC distribution.
Multimodal Treatment Study of Children With ADHD
Links a 14-month randomized treatment phase in childhood ADHD to subsequent follow-up assessments. Analyze the randomized phase and observational follow-up separately. Record-level access requires NDA approval.
Healthy Brain Network Biobank
Youth MRI, EEG and eye tracking have an open access route. Full phenotypes and diagnoses require approval of an institution-signed data use agreement. The provider still displays its October 21, 2026 notice of a temporary LORIS outage.
CATIE Schizophrenia Trial
A multisite trial comparing antipsychotic treatments for schizophrenia. Study treatment assignment, discontinuation and follow-up using the trial definitions. Archived records and some study documents are available to approved researchers.
COBRE Schizophrenia Imaging Dataset
MRI scans, acquisition parameters and phenotypes from schizophrenia and comparison groups. The download route requires a NITRC account and a request to join the INDI project. Attribution and noncommercial use terms apply.
Human Connectome Project for Early Psychosis
Behavioral data for affective and non-affective early psychosis and matched controls, with MRI for a subset. The release documents which participants have each modality. Record-level data require NDA approval.
AMP SCZ · longitudinal psychosis risk study
Release documentation covers clinical and behavioral measures, MRI and EEG in a study of clinical high risk for psychosis. Participant records require approved NDA Data Use Certification.
B-SNIP 1
Intermediate phenotypes from people with schizophrenia or psychotic bipolar disorder and their relatives. The design supports analyses across diagnoses that account for family structure. Record-level data require NDA approval.
STEP-BD
Long-term outpatient research on the course of bipolar disorder, including recurrence. Distinguish the observational cohort from the individual randomized trials when defining an analysis. NDA approval is required for research access.
BD² Integrated Network
The first release, announced in March 2026, combines clinical, biological, imaging and real-world behavioral measures. Qualified researchers apply to BD² for access to participant data.
PsychENCODE
Gene expression and regulation data from postmortem human brain tissue. Processed summaries are public. Controlled human datasets have moved from Synapse to NDA, where each required permission group needs a separate request.
Autism Brain Imaging Data Exchange II
A second multisite ABIDE release with more detailed autism phenotypes and repeat visits in some collections. Use the NITRC imaging download route and follow its registration and usage requirements.
SPARK Autism Research Cohort
Genomic, developmental and behavioral data from autistic participants and their families. SFARI Base reviews data requests by project. Researchers interested in recruiting participants for a new study can apply through Research Match.
Simons Simplex Collection
Links genomic, developmental and behavioral data in families with one autistic child. Request data through SFARI Base. Recontact of families who opted in requires Research Match approval.
AURORA Trauma Follow-up Study
Longitudinal follow-up after trauma in a sample recruited through emergency departments. Check release coverage for mental health assessments, cognitive measures and physiological measures. Participant-level access requires NDA approval.
PTSD Trials Standardized Data Repository
Study-level design and outcome data extracted from published randomized PTSD treatment trials. The repository offers downloads for systematic reviews and meta-analyses.
PGC–ENIGMA PTSD Imaging Working Group
A research network for multisite PTSD imaging meta-analyses and pooled analyses. The working group lists contacts and analysis tools. Discuss cohort participation and data use with the working group.
OCD Collaborative Genetics Association Study
A collaborative genomic study of early-onset OCD. The study overview and phenotype documentation are public. Individual genotypes and phenotypes require dbGaP authorization under the study's use restrictions.
Global OCD Brain Imaging Consortium
A multisite study of brain circuitry and obsessive-compulsive symptom profiles. Check the archive for shared assessments and imaging measures. Participant records require NDA permission.
ENIGMA-OCD Working Group
A working group comparing pediatric and adult OCD imaging across sites. It lists active projects and contacts for contributing a cohort. Data contribution and analysis participation are arranged with the group.
Polish Adolescent Environmental Sensitivity Dataset
Data from an early-adolescent study using the Polish Highly Sensitive Child Scale. The data are licensed CC BY 4.0 and the paper describes the sample and scoring. The scale measures environmental sensitivity as a trait.
Polish Workplace Sensory Processing Sensitivity Dataset
Online survey of 185 Polish civilian employees from 2022–2024. Scores for the HSPS-10, work experience, life satisfaction and burnout are available with a codebook under CC BY 4.0. Some copyrighted questionnaire wording is excluded.
National Mental Health Survey of Korea 2021
Structured interviews with Korean adults include depression, anxiety, obsessive-compulsive and post-traumatic stress measures. Access to microdata requires an application with IRB documentation and review by the data access committee.
National Mental Health Survey of Korea · Child and Adolescent 2022
A nationwide survey of children and adolescents in Korea, with interview measures of attention and hyperactivity, mood, anxiety, compulsions and post-traumatic symptoms. The survey report is public. Microdata require project review and approval.